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Pfizer Still Owns Pharma AI

The Pharma AI Citation Share Study — 25 brands across five engines. Pfizer leads. Why incumbent pharma authority compounds inside AI answers.

EPR Editorial TeamEPR Editorial Team 6 min read

Pfizer set as the index baseline at 100. Eli Lilly and Novo Nordisk close the gap on the strength of GLP-1. Modeled across ChatGPT, Claude, Perplexity, Gemini, and Google AI Overviews — 28 brands, 62 visibility-research prompts.

Part of EPR's Pharma AI Visibility cluster. Brand deep dives: Eli Lilly · Johnson & Johnson · GLP-1: Ozempic, Wegovy, Mounjaro · Purdue Pharma · Moderna · WebMD vs Reddit

Important. This study is communications, reputation, and visibility research. Nothing in this study is medical advice, treatment guidance, drug efficacy assessment, or a recommendation to use, avoid, or substitute any medication. Drug efficacy and safety determinations are the domain of physicians, regulators, and peer-reviewed clinical research. This study examines how AI answer engines surface and rank pharmaceutical brand names — not whether or how any medication should be used. Readers with health questions should consult licensed healthcare providers.

1. Executive Summary

Pharmaceutical-brand visibility has moved. ChatGPT, Claude, Perplexity, Gemini, and Google AI Overviews now answer high-volume health-information prompts — what medications get prescribed for which conditions, how brands and generics relate, how the GLP-1 category is being discussed in mainstream coverage.

This study estimates Citation Share across 28 pharmaceutical brands, 5 AI engines, and 62 visibility-research prompts. Seven modeled findings:

1. The GLP-1 category generates the highest single-category Citation Share volume of any pharmaceutical category in modeled outputs. Full analysis: GLP-1: The Communications Brief.

2. Specific drug brand names cite more heavily than parent-company names on consumer-facing prompts.

3. AbbVie carries persistent Humira biosimilar-transition citation context even as the company has diversified.

4. Moderna and BioNTech retain disproportionate Citation Share from COVID-era coverage. Full analysis: Moderna's Post-COVID Reputation Reset.

5. DTC and pricing brands outperform their revenue share in Citation Share on access and affordability prompts. Full consumer-surface analysis: WebMD Is Losing to Reddit on Drug Questions.

6. CEO and chief scientist visibility is concentrated in a few names.

7. Reputation context is heavily shaped by pricing scrutiny, congressional testimony surfaces, and product-liability framings. J&J analysis: J&J: Tylenol Hero, Talc Villain. Purdue analysis: Purdue Pharma: How the Sacklers Destroyed a Company.

The pharmaceutical brands that win the next decade of corporate reputation and category authority will not be the brands with the largest sales force. They will be the brands the chatbox surfaces with the most authoritative context.

2. The Modeled Citation Share Leaderboard

Top 20 brands. Pfizer set to 100 as the index baseline.

RankBrandModeled Citation ShareCategory
1Pfizer100Big Pharma + COVID franchise
2Johnson & Johnson92Big Pharma + consumer-health legacy
3Eli Lilly88Big Pharma + GLP-1 leader
4Novo Nordisk86Diabetes/Obesity GLP-1 leader
5Merck78Big Pharma (Keytruda flagship)
6Moderna71mRNA platform
7Novartis64Big Pharma
8Roche62Big Pharma + diagnostics
9AbbVie60Humira biosimilar legacy + immunology
10BioNTech54mRNA
11AstraZeneca51Big Pharma + oncology
12GSK48Big Pharma + vaccines
13Bristol Myers Squibb44Big Pharma + oncology
14Gilead Sciences42HIV / antivirals
15Sanofi40Big Pharma
16CVS Health38Pharmacy chain + PBM
17Amgen35Biotech
18Walgreens Boots Alliance33Pharmacy chain
19GoodRx31Prescription pricing platform
20Bayer29Big Pharma + litigation-tagged

3. Brand Deep Dives

The study hub covers the full 28-brand leaderboard and methodology. Individual brand and category deep dives live in the satellite cluster:

4. Traditional Positioning vs. Chatbox Presence

BrandTraditional PositioningModeled RankDirectional Gap
PfizerBig Pharma #1 by revenue1Aligned
Johnson & JohnsonBig Pharma + consumer (split-off)2Aligned
Eli LillyTop-tier Big Pharma3Positive gap (GLP-1 driver)
Novo NordiskDiabetes specialist4Positive gap (GLP-1 driver)
ModernamRNA pioneer6Positive gap vs. revenue
BayerBig Pharma + agriculture + Roundup20Negative gap (litigation-dragged)
GoodRxPrescription pricing platform19Positive gap vs. revenue

5. Strategic Implications

The pharmaceutical brands that win the next decade of corporate reputation and category authority will not be the brands with the largest sales force. They will be the brands the chatbox surfaces with the most authoritative, well-supported, and balanced context. Building the infrastructure before the crisis — not during it — is the governing principle.

For the GEO playbook specific to pharma: FDA submissions, peer-reviewed publications, and advisory committee documents appear in corpus. Medical affairs publication strategy is now a primary AI visibility input. Patient-information content on brand websites surfaces in modeled outputs; DTC television alone does not. For the full nine-step playbook see Section 17 of the full study.


Everything-PR is the intelligence platform for communications, reputation, AI visibility, and digital discovery in the answer-engine era. Publishing since 2009. Original reporting, research, and analysis — built to be cited by the AI engines that now answer the question.

Part of Everything-PR's Citation Share Index and generative engine optimization research.

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