Jim Weiss founded Real Chemistry as a one-person consultancy in San Francisco in 2001. By 2024, the firm hit $665 million and briefly overtook Edelman as the largest U.S. PR firm by revenue. The bet most PR firms missed.
Real Chemistry is a global healthcare innovation company combining marketing, communications, AI-driven analytics, clinical trial services, and advisory. Founded in 2001 by Jim Weiss, it rebranded from W2O Group in 2021. Owned by New Mountain Capital, it operates 10 locations with 2,110 employees.
The top-ranked public relations agencies in 2026 \u2014 the holding-company networks (Omnicom, WPP, Publicis, IPG, Stagwell), the largest independents (Real Chemistry, Edelman, FGS Global), the M&A specialists (Joele Frank, Brunswick, Kekst CNC), and the AI Communications challengers. The EPR reference.
Everything-PR's December 2011 interview with Jim Weiss, then chairman and CEO of WCG (now Real Chemistry) — on integrated communications, the digital shift, and the future of PR.