Unlock Health is a Nashville healthcare marketing agency that serves hospitals, health systems and other large physician organizations, backed by the private equity firms Amulet Capital Partners and Athyrium Capital Management. PRovoke Media's 2024 Global 250 ranking lists it 40th, with 343 staff and $94.2 million in 2023 fee income. Greg Walsh became CEO in May 2026, succeeding co-founder Brandon Edwards.
Updated: October 27, 2026
Contents
What does Unlock Health do?
Unlock Health provides healthcare marketing, performance media, digital technology, analytics and strategic consulting for healthcare organizations. Its May 2026 CEO announcement describes it as the largest fully integrated healthcare marketing agency serving hospitals, health systems and other large physician organizations.
- Healthcare marketing and brand work for providers.
- Performance media planning and buying.
- Digital technology and analytics.
- Managed care and revenue strategy consulting.
The company works with hospitals, health systems, physician organizations, healthcare associations and health technology companies. Its focus on providers separates it from PR-led health specialists such as Spectrum Science, which concentrates on health and science communications.
Who owns and leads Unlock Health?
Unlock Health is backed by two healthcare-focused investors, Amulet Capital Partners, a middle-market private equity firm, and Athyrium Capital Management, a specialized asset manager. Adweek reported in November 2023 that both firms back the company, which was formed in April 2023.
Greg Walsh was named CEO on May 13, 2026, according to the company's announcement. Walsh previously held senior leadership roles at Interpublic Group and Havas. Co-founder and former CEO Brandon Edwards remains on the board and supports consulting and strategic advisory work. In 2023, Shannon McIntyre Hooper was president of Unlock Health.
How big is Unlock Health?
PRovoke Media's 2024 Global 250 ranking lists Unlock Health 40th with $94,155,000 in 2023 fee income and 343 staff. The ranking uses 2023 figures, so it is a year older than the U.S. O'Dwyer's data used for other profiles.
| Measure | Detail |
|---|
| Formed | April 2023 |
| Headquarters | Nashville, TN (company announcement) |
| Staff | 343 (PRovoke Media 2024 ranking) |
| 2023 fee income | $94,155,000 (PRovoke Media 2024 ranking) |
| PRovoke 2024 global rank | 40th |
| Ownership | Backed by Amulet Capital Partners and Athyrium Capital Management |
Adweek reported at the time of the SPM Group deal in November 2023 that Unlock Health had $100 million in revenue and more than 350 clients across provider, behavioral health and dental sectors. The figures differ because the ranking and the company measure revenue differently. The full list is on the PRovoke Media 2024 Global 250.
Which clients is Unlock Health known for?
Unlock Health serves hospitals, health systems and physician groups, and it publishes client case studies on its site. A case study for Norton Healthcare appeared on its resources page on October 20, 2026.
The company's announcements describe more than 350 clients as of November 2023, spanning healthcare provider, behavioral health, dental and associated sectors. It has not published a full client list in the sources reviewed for this profile.
What are Unlock Health's recent moves?
Unlock Health's recent moves are its April 2023 formation, the November 2023 SPM Group acquisition and the May 2026 CEO change. The table lists them newest first.
| Date | Move |
|---|
| May 13, 2026 | Greg Walsh named CEO; co-founder Brandon Edwards stays on the board |
| November 28, 2023 | Acquires SPM Group (SPM, GLC, Dreamscape and Centretek) from Corridor Capital |
| April 2023 | Formed through the acquisition of Eruptr and Decode |
Details are in Adweek's report Unlock Health Acquires SPM Group.
How does Unlock Health compare with peers?
Unlock Health reports fee income close to Supreme Group's scale and above Spectrum Science's, though the sources and years differ. The table notes the source for each figure.
| Firm | Base | Focus | Fees (source) | Staff (source) |
|---|
| Unlock Health | Nashville, TN | Provider healthcare marketing | $94.2M, 2023 (PRovoke) | 343 (PRovoke) |
| Supreme Group | Dallas, TX | Healthcare and life sciences platform | $115.0M, 2025 (O'Dwyer's) | 227 (O'Dwyer's) |
| Spectrum Science | Washington, DC | Health and science communications | $88.1M, 2025 (O'Dwyer's) | 313 (O'Dwyer's) |
| EvolveMKD agency profile | New York, NY | Healthcare, aesthetics and beauty | Not in O'Dwyer's 2026 top 140 | Not listed |
For a wider shortlist by need, see the best healthcare PR agencies ranking, and for every firm profiled on the site, the PR firms directory.
